Pain Relief Meds The most popular Pain Relief medicine today: Butalbital Butalbital is prescribed for the relief of tension headache symptoms caused by muscle contractions in the head, neck, and shoulder area. Celebrex Celebrex is a nonsteroidal anti-inflammatory drug (NSAID) known as a COX-2 inhibitor. It is used to relieve pain and swelling (inflammation). It is used to treat arthritis, acute pain, and menstrual pain and discomfort. Celebrex is also used to decrease growths found in the intestines (colon polyps) in persons with a family history of this condition. This drug works by blocking the enzyme in your body that makes prostaglandins. Decreasing prostaglandins helps to reduce pain and swelling. Esgic Esgic know as acetaminophen, butalbital, and caffeine togetherare used to relieve complex tension (muscle contraction) headaches although precisely how it works is unknown. Fioricet Fioricet know as acetaminophen, butalbital, and caffeine together are used to relieve complex tension headaches although precisely how it works is unknown. Hydrocodone Hydrocodone relieves pain and most commonly used to relieve moderate-to-severe pain; may also be used for purposes other than those listed here. Imitrex Imitrex is a headache medicine. It is believed to work by causing vasoconstriction (narrowing) of arteries and veins that supply blood to your head. Imitrex tablets are used to treat vascular headaches such as migraine and cluster headaches. Imitrex will not prevent migraines or cluster headaches or reduce the number of attacks. It will only treat a migraine or cluster headache that is already occurring. Tramadol Tramadol is used to relieve moderate to moderately severe pain. It also may be used to treat pain caused by surgery and chronic conditions such as cancer or joint pain. Ultracet Ultracet is a unique pain medication that combines tramadol, a leading prescription pain reliever, and acetaminophen, the most commonly recommended over-the-counter analgesic in the U.S. Ultracet has been approved for the short-term (five days or less) management of acute pain. Ultram Ultram Drug is an analgesic used to treat or prevent pain. Vicodin Vicodin is a complex acetaminophen and hydrocodone. Hydrocodone relieves pain. Acetaminophen is a less potent pain reliever that increases the effects of hydrocodone. Together, acetaminophen and hydrocodone are most commonly used to relieve moderate-to-severe pain. Vioxx The Drug Vioxx is a nonsteroidal anti-inflammatory drug (NSAID) known as a COX-2 inhibitor used to relieve the symptoms of osteoarthritis and to treat pain and menstrual discomfort. Zebutal Zebutal knowing as complex acetaminophen, butalbital, and caffeine are used to relieve complex tension (muscle contraction) headaches. Acetaminophen is a pain reliever and fever reducer. Butalbital is in a class of drugs called barbiturates that slow down your central nervous system (brain and nerve impulses) causing relaxation. Caffeine is believed to constrict dilated blood vessels that may contribute to tension headaches.